Posted on July 2, 2021: Dr. Brandon Choi’s research lab is looking for 2-3 highly motivated undergraduate students to join our research group in the fall of 2021. The Choi lab studies how protein conformations are affected by devastating neurodegenerative diseases such as Parkinson’s, Alzheimer’s, and Huntington’s. We use the cutting-edge single-molecule microscopy technique called smFRET (single-molecule fluorescence resonance energy transfer) to identify and characterize the dynamic structures and protein-protein interactions of various proteins such as alpha-synuclein, amyloid beta, HTT, and SNAREs.
Requirements: Previous research experience in biochemistry, biology, or physics is preferred, but the most important factor is enthusiasm and motivation in doing research. We expect at least a one year commitment from undergraduate researchers. Depending on the undergraduate’s research experience, we expect a time commitment of at least 3 hours for 2-3 days per week (6-9 hours per week on average).
This research can be undertaken on a volunteer basis, for course credit (e.g., Honors 497 credit or 497 credit within student’s major), as part of a WVU capstone project (e.g., Honors EXCEL), or within an academic year program (e.g., RAP). This research experience is expected to lead to continued involvement in research during Summer 2022 and potentially supported by a WVU research program (e.g., SURE).
Benefits: In the Choi lab, students will learn protein engineering, expression, purification, labeling and, the most exciting part, imaging single-molecules to understand the motions of protein molecules, and conformational pathways that lead to human diseases. In addition, undergraduate students will participate in scientific meetings (BPS, ASBMB, SFN), be involved in writing manuscripts, and collaborate with other research groups in and outside of WVU to develop their network.
Location and Specifics: We are located in Health Science Center North, Room 3096, in the School of Medicine. Please contact Dr. Brandon Choi at Ucheor.choi@hsc.wvu.edu or (304)293-1508 if you are interested in learning more about this opportunity. More information about our research can be found at: https://ucheorchoi.wixsite.com/mysite-1
Note: The Choi lab is also looking for a full-time, 12-month research technician. This position would be for best for someone who has graduated and would like some research experience before entering graduate, medical or health professional school. At least a 2-year commitment is expected for research technicians, though the time period can be extended. Annual salary would depend on experience. Contact Dr. Choi, if interested.
